The tomb of Thutmes IV is generally similar to that of Amenhetep II, but it has a second right-angle turn in the axis just before the burial chamber, and the distribution of its decoration is different. The tomb is especially well cut in good quality limestone bedrock. The tomb was entered in 1903 by Howard Carter. He found numerous objects inside and two collections of foundation deposits placed in small pits cut just outside the tomb entrance.
The only decoration in KV 43 is on the walls of the well chamber and the chamber preceding the burial chamber. The former consists of scenes of Thutmes IV being given an ankh sign by Osiris, Anubis, and Hathor. Unlike similar scenes in the tomb of Amenhetep II (KV 35), these are well painted, not just outlined. Hathor, for example, wears an elaborately patterned dress, a different pattern in each of her three representations. The headdresses and costumes of other figures are equally well done. Inside the tomb, a rope used by ancient thieves still lay in the first pillared chamber, tied around one of the pillars and hanging into the preceding well shaft. Apparently, several robberies had taken place here in antiquity, and during the reign of  Horemheb a court official was commanded to inspect the tomb and reseal it. The official responsible, Maya, left a beautifully calligraphic record of his tour on the right (south) wall of the chamber just before the burial chamber: “Year 8…His Majesty commanded that the fanbearer on the king’s right hand, the royal scribe, overseer of the treasury, overseer of works in the palace of eternity and leader of the festival of Amen in Karnak, Maya, son of the noble Iawy, born of the lady of the house Weret, be charged to renew the burial of king [Thutmes IV], true of voice, in the noble mansion upon the west of Thebes.” The decoration on three walls of this chamber is similarly painted to what was found in the well chamber and includes the same deities. This is the first tomb in the Valley of the Kings to have such scenes.
The burial chamber, like that in KV 35, was cut on two levels with six pillars on the upper level and a central staircase leading to the lower. There is no decoration in the burial chamber, only a red-painted quartzite sarcophagus at the far end of the chamber. It is decorated with finely carved hieroglyphs. Four magical brick niches are cut in the lower part of the chamber, one on each of its walls, a fourth in the rear face of the left pillar. Fourside chambers, two cut into the side walls of the upper level, two into the side walls of the lower, were closed by wooden doors in ancient times and contained food offerings and various funerary objects. The way in which the tomb was quarried, together with the small number of decorated walls, suggests that Thutmes IV had been buried in haste.